Reversible cerebral lesions associated with tiazofurin usage: MR demonstration

J Comput Assist Tomogr. Nov-Dec 1988;12(6):1078-81. doi: 10.1097/00004728-198811000-00037.

Abstract

Tiazofurin is an experimental chemotherapeutic agent currently undergoing clinical evaluation. We report our results with magnetic resonance (MR) in demonstrating reversible cerebral abnormalities concurrent with the use of this drug. The abnormalities on MR were correlated with findings on CT as well as with cerebral angiography. The utility of MR in the evaluation of patients receiving this new agent is illustrated.

Publication types

  • Case Reports

MeSH terms

  • Antineoplastic Agents / adverse effects*
  • Brain Diseases / chemically induced*
  • Brain Diseases / diagnosis*
  • Female
  • Humans
  • Magnetic Resonance Imaging*
  • Middle Aged
  • Ribavirin / adverse effects*
  • Ribavirin / analogs & derivatives
  • Ribonucleosides / adverse effects*

Substances

  • Antineoplastic Agents
  • Ribonucleosides
  • Ribavirin
  • tiazofurin