Induced pluripotent stem cell line (PEIi003-A) derived from an apparently healthy male individual

Stem Cell Res. 2020 Jan;42:101679. doi: 10.1016/j.scr.2019.101679. Epub 2019 Dec 4.

Abstract

Induced pluripotent stem cells (iPSCs) are a useful tool to investigate pathomechanistic and cellular processes due to their differentiation potential into different somatic cell types in vitro. Here, we have generated iPSCs from an apparently healthy male individual using an integration-free reprogramming method. The resulting iPSCs are pluripotent and display a normal karyotype. Furthermore, we demonstrate that this iPSC line can be differentiated into all three germ layers.

Keywords: Induced Pluripotent stem cells capable of differentiation into all three germ layers; Induced pluripotent stem cells from an apparently healthy individual.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Cell Differentiation
  • Healthy Volunteers
  • Humans
  • Induced Pluripotent Stem Cells / metabolism*
  • Male