Effect of vitamin A treatment on the immune reactivity of patients with systemic lupus erythematosus

J Clin Lab Immunol. 1988 May;26(1):33-5.

Abstract

Treatment of patients suffering from systemic lupus erythematosus with vitamin A (100,000 U daily for 2 weeks) resulted in an enhancement of antibody-dependent cell-mediated cytotoxicity, natural killer cell activity and blastogenic response to plant mitogens and interleukin-2 (IL-2).

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Antibody-Dependent Cell Cytotoxicity / drug effects
  • Female
  • Humans
  • Immunity, Cellular / drug effects*
  • In Vitro Techniques
  • Killer Cells, Natural / drug effects
  • Lupus Erythematosus, Systemic / drug therapy*
  • Lupus Erythematosus, Systemic / immunology
  • Lymphocyte Activation / drug effects
  • Mitogens / pharmacology
  • Vitamin A / administration & dosage
  • Vitamin A / therapeutic use*

Substances

  • Mitogens
  • Vitamin A