Practical Applications of Biofluorescent Particle Counting in Environmental Monitoring Investigations

PDA J Pharm Sci Technol. May-Jun 2020;74(3):318-323. doi: 10.5731/pdajpst.2019.009969. Epub 2019 Dec 16.

Abstract

Investigations into environmental monitoring (EM) excursions can be prolonged and do not always result in clear root causes or corrective and preventative actions. This article outlines how biofluorescent particle counting (BFPC) can be used in investigations to eliminate the inherent delays of culture-based methods. The application for investigations supplements routine EM, acting as a risk-reduction tool enabling real-time detection of viable microorganisms in air samples and supporting root cause analysis and remedial actions. The article includes guidance on how to use the technology, a real case study involving a mold excursion, and examples of business benefits achieved by various companies.

MeSH terms

  • Air Filters / standards*
  • Air Microbiology / standards*
  • Drug Contamination / prevention & control*
  • Environmental Monitoring / methods
  • Environmental Monitoring / standards*
  • Fluorescent Dyes / analysis*
  • Humans
  • Particle Size*

Substances

  • Fluorescent Dyes