Precision surgery in lung metastasectomy

Future Oncol. 2020 Jun;16(16s):7-13. doi: 10.2217/fon-2018-0713. Epub 2019 Dec 20.


The value of pulmonary metastasis (PM) resection in the context of controlled primary tumor sites was shown to improve survival of patients if complete resection could be achieved. The surgeon's approach can be modulated by various parameters pertaining to safety margins including local growth properties, size, spread and location of PMs. Lymph node dissection and assessment is recommended although its impact on survival remains unclear. Thoracoscopic surgery combined to thin slice chest CT scans has shown results comparable to thoracotomy in patients with few PMs. The management of PMs should therefore be discussed on an individual, interdisciplinary basis to offer the best possible oncological and surgical results as well as to maximize long term patient survival rates.

Keywords: FDG-PET; colorectal cancer; pulmonary anatomical resection; pulmonary metastasectomy; pulmonary metastases; thoracoscopy.

Publication types

  • Review

MeSH terms

  • Biomarkers, Tumor / analysis
  • Chemotherapy, Adjuvant
  • Clinical Decision-Making
  • Colorectal Neoplasms / diagnosis
  • Colorectal Neoplasms / mortality
  • Colorectal Neoplasms / pathology
  • Colorectal Neoplasms / therapy*
  • Disease-Free Survival
  • Humans
  • Lung / diagnostic imaging
  • Lung / pathology
  • Lung / surgery
  • Lung Neoplasms / diagnosis
  • Lung Neoplasms / mortality
  • Lung Neoplasms / secondary
  • Lung Neoplasms / therapy*
  • Lymph Node Excision
  • Lymph Nodes / pathology
  • Lymph Nodes / surgery
  • Lymphatic Metastasis / diagnosis
  • Lymphatic Metastasis / pathology
  • Margins of Excision
  • Patient Selection
  • Pneumonectomy / methods*
  • Prognosis
  • Thoracic Surgery, Video-Assisted / methods*
  • Tomography, X-Ray Computed


  • Biomarkers, Tumor