[Clinical and epidemiological characterization of healthcare acquired influenza in critical ill patients]

Rev Chilena Infectol. 2019 Jun;36(3):274-282. doi: 10.4067/S0716-10182019000300274.
[Article in Spanish]

Abstract

Background: Healthcare-associated infections (HAIs) increase morbidity and mortality. During 2014, at the Hospital Clinico Red de Salud UC Christus (RS-UCCH) it was estimated that 15% of respiratory viral infections were acquired during hospitalization and influenza A was more frequent.

Aims: Clinical and epidemiological characterization of HAIs due to influenza virus in patients hospitalized in critical care units (CCU) and special care.

Methods: Descriptive study. We included patients hospitalized in CCU and special care with hospital acquired influenza during 2014-2017. HAI due to influenza was defined as: symptom onset and/or positive influenza PCR after ≥ 48 hours of hospital admission, without previous respiratory symptoms or previous negative influenza test study.

Results: 22 patients were identified, median age was 74 years. Influenza was acquired average on day 13. Influenza A was detected in 77% and 27% had respiratory co-infection. Thirteen (59%) were hospitalized in CCU, only 2 (15%) due to lung problems. Comorbidity was present in 86% and decompensation in 50%. Only 41% received influenza vaccine. The associated lethality was 18%.

Conclusions: HAI due to influenza occurred in chronic, older and unvaccinated patients. Education about HAIs and continuous high vaccination coverage must be reinforced.

MeSH terms

  • Adolescent
  • Adult
  • Age Factors
  • Aged
  • Aged, 80 and over
  • Child
  • Child, Preschool
  • Chile / epidemiology
  • Comorbidity
  • Critical Care
  • Cross Infection / diagnosis
  • Cross Infection / epidemiology*
  • Cross Infection / prevention & control
  • Female
  • Hospitalization / statistics & numerical data
  • Humans
  • Infant
  • Influenza Vaccines
  • Influenza, Human / diagnosis
  • Influenza, Human / epidemiology*
  • Influenza, Human / prevention & control
  • Intensive Care Units / statistics & numerical data*
  • Male
  • Middle Aged
  • Young Adult

Substances

  • Influenza Vaccines