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, 9 (1), 19715

Predictive Factors for Inadequate Bowel Preparation Using Low-Volume Polyethylene Glycol (PEG) Plus Ascorbic Acid for an Outpatient Colonoscopy

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Predictive Factors for Inadequate Bowel Preparation Using Low-Volume Polyethylene Glycol (PEG) Plus Ascorbic Acid for an Outpatient Colonoscopy

Seung Yong Shin et al. Sci Rep.

Abstract

Low-volume polyethylene glycol (PEG) plus ascorbic acid solutions are widely used for bowel cleansing before colonoscopy. This study aimed to investigate the pre-endoscopic predictive factors for inadequate preparation in subjects receiving low-volume PEG plus ascorbic acid. A prospective study was performed at Gangnam Severance Hospital, Korea, from June 2016 to December 2016. All participants received low-volume PEG plus ascorbic acid solutions for outpatient colonoscopy. The split-dose bowel preparation was administered in subject with morning colonoscopy while same day bowel preparation was used for afternoon colonoscopy. 715 patients were enrolled (mean age 56.1 years, 54.4% male), of which 138 (19.3%) had an inadequate bowel preparation. In multivariable analysis, cirrhosis (OR 4.943, 95% CI 1.191-20.515), low (less than 70%) compliance for three-day low-residual diet (OR 2.165, 95% CI 1.333-3.515), brown liquid rectal effluent (compared with clear or semi-clear effluent) (OR 7.604, 95% CI, 1.760-32.857), and longer time interval (≥2 hours) between last defecation and colonoscopic examination (OR 1.841, 95% CI, 1.190-2.849) were found as an independent predictors for inadequate preparation. These predictive factors may be useful in guiding additional intervention to improve quality of bowel preparation.

Conflict of interest statement

The authors declare no competing interests.

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