Preparation of paclitaxel-folic acid functionalized gelatin grafted mesoporous hollow carbon nanospheres for enhancing antitumor effects toward liver cancer (SMMC-7721) cell lines

J Biomater Appl. 2020 Mar;34(8):1071-1080. doi: 10.1177/0885328219896457. Epub 2019 Dec 26.
No abstract available

Keywords: Mesoporous hollow carbon nanosphere; anticancer activity; folic acid; gelatin; paclitaxel; tumor-targeted.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Antineoplastic Agents / chemistry*
  • Antineoplastic Agents / pharmacology
  • Apoptosis / drug effects
  • Carbon / chemistry*
  • Cell Line, Tumor
  • Cell Membrane Permeability
  • Drug Compounding
  • Drug Liberation
  • Folic Acid / chemistry*
  • Folic Acid / metabolism
  • Gelatin / chemistry*
  • Heterografts
  • Humans
  • Liver Neoplasms / drug therapy*
  • Mice
  • Nanospheres / chemistry*
  • Neoplasms, Experimental
  • Paclitaxel / chemistry*
  • Paclitaxel / pharmacology
  • Porosity
  • Surface Properties

Substances

  • Antineoplastic Agents
  • Carbon
  • Gelatin
  • Folic Acid
  • Paclitaxel