Hürthle Cell Thyroid Adenoma Showing Avid Uptake on 18F-PSMA-1007 PET/CT

Clin Nucl Med. 2020 Mar;45(3):223-224. doi: 10.1097/RLU.0000000000002873.

Abstract

We report the case of a 74-year-old man with suspected recurrent prostate carcinoma who underwent F-PSMA-1007 PET/CT for restaging the disease. PET/CT imaging presented an incidentaloma with intense F-PSMA-1007 uptake in the right thyroid lobe. Biopsy and genomic sequencing test confirmed the diagnosis of Hürthle cell thyroid adenoma. Therefore, it is important to raise awareness of this benign lesion in the differential diagnosis of incidental thyroid nodules with high F-PSMA-1007 activity.

Publication types

  • Case Reports

MeSH terms

  • Adenoma, Oxyphilic / complications
  • Adenoma, Oxyphilic / diagnostic imaging*
  • Adenoma, Oxyphilic / metabolism*
  • Aged
  • Biological Transport
  • Fluorine Radioisotopes*
  • Humans
  • Male
  • Neoplasm Staging
  • Niacinamide / analogs & derivatives*
  • Niacinamide / metabolism
  • Oligopeptides / metabolism*
  • Positron Emission Tomography Computed Tomography*
  • Prostatic Neoplasms / complications
  • Prostatic Neoplasms / diagnostic imaging
  • Prostatic Neoplasms / pathology
  • Thyroid Neoplasms / complications
  • Thyroid Neoplasms / diagnostic imaging*
  • Thyroid Neoplasms / metabolism*

Substances

  • Fluorine Radioisotopes
  • Oligopeptides
  • PSMA-1007
  • Niacinamide
  • Fluorine-18