By-Products of Camu-Camu [ Myrciaria dubia (Kunth) McVaugh] as Promising Sources of Bioactive High Added-Value Food Ingredients: Functionalization of Yogurts

Molecules. 2019 Dec 24;25(1):70. doi: 10.3390/molecules25010070.


Camu-camu (Myrciaria dubia (Kunth) McVaugh) is a fruit economically relevant to the Amazon region, mostly consumed in the form of processed pulp. Our aim was to perform an unprecedented comparative study on the chemical composition and bioactivities of the camu-camu pulp and industrial bio-residues (peel and seed), and then the most promising fruit part was further explored as a functionalized ingredient in yogurt. A total of twenty-three phenolic compounds were identified, with myricetin-O-pentoside and cyanindin-3-O-glucoside being the main compounds in peels, followed by p-coumaroyl hexoside in the pulp, and ellagic acid in the seeds. The peel displayed the richest phenolic profile among samples, as well as the most significant antibacterial (MICs = 0.625-10 mg/mL) and anti-proliferative (GI50 = 180 µg/mL against HeLa cells) activities. For this reason, it was selected to be introduced in a food system (yogurt). Taken together, our results suggest the possibility of using the camu-camu peel as a source of food additives.

Keywords: Myrciaria dubia; anti-proliferative effects; antibacterial potential; hydroethanolic extracts; phenolic composition.

MeSH terms

  • Anti-Infective Agents / pharmacology
  • Cell Proliferation / drug effects
  • Fatty Acids / analysis
  • Food Ingredients*
  • Microbial Sensitivity Tests
  • Myrtaceae / chemistry*
  • Phenols / analysis
  • Plant Extracts / pharmacology
  • Sugars / analysis
  • Yogurt / analysis*


  • Anti-Infective Agents
  • Fatty Acids
  • Food Ingredients
  • Phenols
  • Plant Extracts
  • Sugars