Comparing a Distributed Parameter Model-Based System Identification Technique with More Conventional Methods for Inverse Problems

J Inverse Ill Posed Probl. 2019 Oct;27(5):703-717. doi: 10.1515/jiip-2018-0006. Epub 2019 Feb 16.

Abstract

Three methods for the estimation of blood or breath alcohol concentration (BAC/BrAC) from biosensor measured transdermal alcohol concentration (TAC) are evaluated and compared. Specifically, we consider a system identification/quasi-blind deconvolution scheme based on a distributed parameter model with unbounded input and output for ethanol transport in the skin and compare it to two more conventional system identification and filtering/deconvolution techniques for ill-posed inverse problems, one based on frequency domain methods, and the other on a time series approach using an ARMA input/output model. Our basis for comparison are five statistical measures of interest to alcohol researchers and clinicians: peak BAC/BrAC, time of peak BAC/BrAC, the ascending and descending slopes of the BAC/BrAC curve, and the area underneath the BAC/BrAC curve.

Keywords: 35K90; 47D06; 65M32; 92C55; 93B30; 93C20; Blind deconvolution; Distributed parameter systems; Filtering; See www.ams.org/msc; System identification; Transdermal alcohol biosensor.