Multifocal and multicentric breast cancer, is it time to think again?

Ann R Coll Surg Engl. 2020 Jan;102(1):62-66. doi: 10.1308/rcsann.2019.0109. Epub 2019 Sep 6.

Abstract

Multifocal multicentric breast cancer has traditionally been considered a contraindication to breast conserving surgery because of concerns regarding locoregional control and risk of disease recurrence. However, the evidence supporting this practice is limited. Increasingly, many breast surgeons are advocating breast conservation in selected cases. This short narrative review summarises current evidence on the role of surgery in multifocal multicentric breast cancer and shows that when technically feasible the option of breast conservation is oncologically safe.

Keywords: Breast conserving surgery; Mastectomy; Multicentric; Multifocal; Oncoplastic surgery; breast cancer.

Publication types

  • Meta-Analysis
  • Review

MeSH terms

  • Breast Neoplasms / mortality
  • Breast Neoplasms / secondary*
  • Clinical Decision-Making
  • Epidemiologic Methods
  • Feasibility Studies
  • Female
  • Humans
  • Mastectomy / methods*
  • Mastectomy / mortality
  • Mastectomy, Segmental / methods
  • Mastectomy, Segmental / mortality
  • Practice Patterns, Physicians'
  • Treatment Outcome