Deciphering a delayed hemolytic transfusion reactions nightmare - Case of Chido/Roger antibodies

Asian J Transfus Sci. 2019 Jul-Dec;13(2):132-135. doi: 10.4103/ajts.AJTS_152_17. Epub 2019 Dec 3.

Abstract

Antibodies against Rh (CEce) and Kidd (Jka and Jkb) system antigens are mostly implicated in delayed hemolytic transfusion reactions (DHTR), which is a potentially life-threatening complication observed in patients receiving chronic transfusions. Here, we are describing a case of Chido/Roger antibody which presented to our laboratory as DHTR. The clinical presentation and laboratory findings including the immunohematological workups with regard to the reaction are discussed, with a special emphasis on the benefit of identifying such an antibody and obtaining blood unit for transfusion supports the patient with respect to providing a compatible unit.

Keywords: Chido/roger antibody; delayed hemolytic transfusion reaction; red blood cell transfusion.

Publication types

  • Case Reports