Myocardial perfusion stress test: is it worth?

Int J Cardiovasc Imaging. 2020 Apr;36(4):741-748. doi: 10.1007/s10554-019-01749-9. Epub 2020 Jan 2.

Abstract

To test the utility of the Tc99m-sestaMIBI myocardial perfusion stress test (MPS) over stress echo test (SEHO) in dyslipidemic patients with intermediate pre-test probability score. 56 dyslipidemic patients (42 males and 14 females) with a suspected/known ischaemic heart disease and intermediate pre-test probability score underwent MPS and SEHO. They were followed for 25.77 ± 6.19 months. The data about the new-onset cardiac events and possible coronary angiography (CA) were collected. MPS was positive in 80% of the patients, SEHO in 68% of the patients. Results of the SEHO and MPS showed a good correlation (p < 0.001, μ = 0.505). Both procedures had a good correlation with CA findings in the follow-up. Cardiac events occurred in 57% of the patients. The MPS result, SSS, SDS were significantly associated with the new-onset cardiac events (p < 0.05). The patients with higher SDS had more chance to get a cardiac event in the follow-up (ROC curve area = 0.719, p = 0.003). MPS sensitivity was 91%, specificity 56%; SEHO sensitivity 85% and specificity 61%. MPS may be useful in predicting a future cardiovascular event. It is sufficiently informative, objectified by quantification software, and with correspondingly reduced radiation doses it may be the method of choice in patients with intermediate pre-test probability score.

Keywords: Intermediate pre-test probability score; Myocardial perfusion stress test; SPECT; Stress echo test; Usefulness.

Publication types

  • Comparative Study

MeSH terms

  • Contrast Media / administration & dosage*
  • Disease Progression
  • Dyslipidemias / blood
  • Dyslipidemias / complications*
  • Dyslipidemias / diagnosis
  • Echocardiography, Stress*
  • Exercise Test
  • Female
  • Humans
  • Male
  • Myocardial Ischemia / diagnostic imaging*
  • Myocardial Ischemia / etiology
  • Myocardial Ischemia / physiopathology
  • Myocardial Perfusion Imaging / methods*
  • Predictive Value of Tests
  • Prognosis
  • Reproducibility of Results
  • Technetium Tc 99m Sestamibi / administration & dosage
  • Time Factors
  • Tomography, Emission-Computed, Single-Photon*

Substances

  • Contrast Media
  • Technetium Tc 99m Sestamibi