The first total vertebral involvement of benign fibrous histiocytoma: A case report and literature review

Jian Yang; Nanzhe Zhong; Jinbo Hu; Xinghai Yang; Jianru Xiao

doi:10.1016/j.jbo.2019.100274

The first total vertebral involvement of benign fibrous histiocytoma: A case report and literature review

J Bone Oncol. 2019 Dec 20:20:100274. doi: 10.1016/j.jbo.2019.100274. eCollection 2020 Feb.

Authors

Jian Yang¹, Nanzhe Zhong¹, Jinbo Hu¹, Xinghai Yang¹, Jianru Xiao¹

Affiliation

¹ Department of Orthopedic Oncology, Changzheng Hospital, Second Military Medical University, Fengyang Rd 415#, Huangpu District, Shanghai, China.

Abstract

Background: Benign fibrous histiocytoma (BFH) is a rare bone tumor, extremely seldom in the spine.

Methods: We present a 52-year-old patient diagnosed with a BFH in the thoracic spine treated with total en bloc spondylectomy. A review of the published literature was also conducted.

Results: Non-ossifying fibroma (NOF) and BFH are named as one tumor called NOF/BFH. A total of 20 spinal BFHs have been previously reported, mainly involving the posterior elements. We present a BFH with total vertebral involvement. Curettage and excision are the main treatment options with limited recurrence.

Conclusions: This is the first total vertebral BFH up to now. Spinal BFH occupies rather low aggressiveness. With rather limited recurrence and malignant degeneration, surgical interventions seem enough for its management.

Keywords: Benign fibrous histiocytoma; Non-ossifying fibroma; Spine; Total en bloc spondylectomy; Vertebral.