The therapeutic versatility of antihistamines: A comprehensive review

Nurse Pract. 2020 Feb;45(2):8-21. doi: 10.1097/01.NPR.0000651112.76528.ed.


Antihistamines are common and readily available medications for primary care patients and those seeking over-the-counter treatments. This article provides an overview of available antihistamines, their mechanisms of action, safety concerns in specific populations, and their therapeutic uses in several common conditions.

Publication types

  • Review

MeSH terms

  • Clinical Trials as Topic
  • Histamine Antagonists / therapeutic use*
  • Humans
  • Nurse Practitioners
  • Randomized Controlled Trials as Topic


  • Histamine Antagonists