New Paradigm for Cytoskeletal Organization in Podocytes: Proteolytic Fragments of INF2 Formin Function Independently of INF2 Actin Regulatory Activity

J Am Soc Nephrol. 2020 Feb;31(2):235-236. doi: 10.1681/ASN.2019121292. Epub 2020 Jan 10.

Authors

Mira Krendel¹, David Pruyne²

Affiliations

¹ Department of Cell and Developmental Biology, State University of New York Upstate Medical University, Syracuse, New York.
² Department of Cell and Developmental Biology, State University of New York Upstate Medical University, Syracuse, New York pruyned@upstate.edu.

No abstract available

Keywords: FSGS; INF2; actin; foot process effacement; formin; podocyte.

Publication types

Editorial
Research Support, N.I.H., Extramural
Comment

MeSH terms

Actins
Formins
Glomerulosclerosis, Focal Segmental*
Humans
Microfilament Proteins
Mutation
Podocytes*

Substances

Actins
Formins
INF2 protein, human
Microfilament Proteins

Grant support