Measuring atopic eczema symptoms in clinical practice: The first consensus statement from the Harmonising Outcome Measures for Eczema in clinical practice initiative

J Am Acad Dermatol. 2020 May;82(5):1181-1186. doi: 10.1016/j.jaad.2019.12.055. Epub 2020 Jan 8.


Background: Measuring patient-centered outcomes in clinical practice is valuable for monitoring patients and advancing real-world research. A new initiative from the Harmonising Outcome Measures for Eczema (HOME) group aims to recommend what might be recorded for atopic eczema patients in routine clinical care.

Objectives: Prioritize outcome domains to measure atopic eczema in clinical practice and select valid and practical outcome measurement instruments for the highest-priority domain.

Methods: An online survey of HOME members identified and ranked 21 possible health domains. Suitable instruments were then selected for the top-prioritized domain at the HOME VI meeting, using established consensus processes informed by systematic reviews of instrument quality.

Results: Patient-reported symptoms was the top-prioritized domain. In accordance with psychometric properties and feasibility, there was consensus that the recommended instruments to measure atopic eczema symptoms in clinical practice are the POEM, the PO-SCORAD index, or both. The numeric rating scale for itch received support pending definition and validation in atopic eczema.

Conclusion: Following the first step of the HOME Clinical Practice initiative, we endorse using the POEM, the PO-SCORAD index, or both for measuring atopic eczema symptoms in clinical practice. Additional high-priority domains for clinical practice will be assessed at subsequent HOME meetings.

Keywords: HOME; Harmonising Outcome Measures for Eczema; atopic dermatitis; atopic eczema; clinical practice; eczema; instruments; outcome measures; outcomes.

MeSH terms

  • Consensus*
  • Dermatitis, Atopic / complications
  • Dermatitis, Atopic / diagnosis*
  • Dermatitis, Atopic / psychology
  • Dermatology / standards*
  • Feasibility Studies
  • Humans
  • Patient Outcome Assessment*
  • Pruritus / diagnosis*
  • Pruritus / etiology
  • Pruritus / psychology
  • Psychometrics / standards
  • Quality of Life
  • Severity of Illness Index