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. 2019 Dec 18;14(3):151-158.
doi: 10.15420/ecr.2019.16.2. eCollection 2019 Dec.

Electronic Cigarettes and Cardiovascular Risk: Caution Waiting for Evidence

Free PMC article

Electronic Cigarettes and Cardiovascular Risk: Caution Waiting for Evidence

Domenico D'Amario et al. Eur Cardiol. .
Free PMC article


Electronic cigarettes use is a growing trend in contemporary societies, with the propensity to compete with traditional tobacco smoking. Some preclinical studies demonstrated the toxic and detrimental effects of electronic cigarettes liquid components. Its impact on human health remains unknown and insufficiently studied. While some studies suggest that electronic cigarettes use might be associated with endothelial dysfunction, impaired platelet function and increased risk of adverse clinical events, other studies did not confirm these findings and epidemiological data mostly suggest that the use of electronic cigarettes appears to be safer than that of traditional tobacco cigarettes. This article provides an up-to-date overview of the current state of knowledge regarding electronic cigarettes and their impact on human health, with special emphasis on their effect on cardiovascular diseases.

Keywords: Electronic cigarettes; cardiovascular system; cerebrovascular; health; heart; mortality; risk; smoking; tobacco.

Conflict of interest statement

Disclosure: The authors have no conflicts of interest to declare.


Figure 1:
Figure 1:. Schematic Diagram of Electronic Cigarette System
Figure 2:
Figure 2:. The Physiological Effects of Electronic Cigarette Inhalation on the Heart and Vasculature

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