Subfoveal Choroidal Thickness and Its Intereye Differences in Fuchs Uveitis Syndrome Evaluated Using Optical Coherent Tomography

Ocul Immunol Inflamm. 2021 Jul 4;29(5):896-901. doi: 10.1080/09273948.2019.1699579. Epub 2020 Jan 16.

Abstract

Purpose: To measure the subfoveal choroidal thickness (SFCT) and assess intereye subfoveal choroidal thickness difference (ISFCTD) in patients with unilateral Fuchs Uveitis Syndrome (FUS) compared with healthy controls.Methods: Forty-two patients with unilateral FUS were included in this observational retrospective study. SFCT in both eyes was measured in patients and controls using optical coherent tomography. The measurements were analyzed and compared as follows: for SFTC-affected eye vs fellow eye (FUS); affected eye (FUS) vs right control eye; fellow eye (FUS) vs left control eye; for ISFCTD - FUS patients vs controls. In addition, measurement error analysis was performed.Results: No significant differences in SFCT between the compared eyes were found (p > .05). The mean ISFCTD was 57.24 ± 40.8 µm in FUS patients and 30.33 ± 25.48 µm in controls (p < .,001).Conclusion: The ISFCTD was higher in FUS patients than in controls. There were no statistically significant differences in SFCT between the compared eyes.

Keywords: Choroidal thickness; Fuchs uveitis syndrome; choroid; choroidal thickness intereye difference; optical coherence tomography.

MeSH terms

  • Adult
  • Choroid / diagnostic imaging
  • Choroid / pathology*
  • Choroid Diseases / diagnosis*
  • Choroid Diseases / diagnostic imaging
  • Choroid Diseases / physiopathology
  • Female
  • Fovea Centralis
  • Humans
  • Iridocyclitis / diagnosis*
  • Iridocyclitis / diagnostic imaging
  • Iridocyclitis / physiopathology
  • Male
  • Middle Aged
  • Organ Size
  • Retrospective Studies
  • Tomography, Optical Coherence
  • Visual Acuity