Age-related differences in the temporal dynamics of spectral power during memory encoding

PLoS One. 2020 Jan 16;15(1):e0227274. doi: 10.1371/journal.pone.0227274. eCollection 2020.

Abstract

We examined oscillatory power in electroencephalographic recordings obtained while younger (18-30 years) and older (60+ years) adults studied lists of words for later recall. Power changed in a highly consistent way from word-to-word across the study period. Above 14 Hz, there were virtually no age differences in these neural gradients. But gradients below 14 Hz reliably discriminated between age groups. Older adults with the best memory performance showed the largest departures from the younger adult pattern of neural activity. These results suggest that age differences in the dynamics of neural activity across an encoding period reflect changes in cognitive processing that may compensate for age-related decline.

Publication types

  • Comparative Study
  • Research Support, N.I.H., Extramural
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Adolescent
  • Adult
  • Age Factors
  • Aged
  • Aged, 80 and over
  • Aging / physiology
  • Brain / physiology*
  • Cognition / physiology*
  • Electroencephalography*
  • Electrophysiological Phenomena
  • Female
  • Humans
  • Male
  • Memory Disorders / physiopathology*
  • Mental Recall / physiology*
  • Middle Aged
  • Time Factors
  • Young Adult