In mirror visual feedback (MVF) based rehabilitation, the illusion of mirror reflection of volitional movement of non-paretic limb tends to have a modulatory effect on visuomotor and sensorimotor brain activations. This paper presents EEG based analysis of hemispheric activation asymmetry within the beta band (15-28 Hz) when MVF is combined with a target-directed hand motor task in a block design versus a similar task without any target requirements. MVF coupled with target-directed movement was associated with a decrease in hemispheric asymmetry in both preparation and execution phases of movement. These results emphasize the potential importance of incorporating visuomotor goals into the task to maximize the rehabilitation outcomes of MVF-based training activities.