Tracking Changes in Brain Network Connectivity under Transcranial Current Stimulation

Annu Int Conf IEEE Eng Med Biol Soc. 2019 Jul:2019:6430-6433. doi: 10.1109/EMBC.2019.8857338.


Noninvasive transcranial brain stimulation has been widely used in experimental and clinical applications to perturb the brain activity, aiming at promoting synaptic plasticity or enhancing functional connectivity within targeted brain regions. However, there are different types of neurostimulations and various choices of stimulation parameters; how these choices influence the intermediate neurophysiological effects and brain connectivity remain incompletely understood. We propose several quantitative methods to investigate the brain connectivity of an epileptic patient before and after transcranial alternating/direct current stimulation (tACS/tDCS). The neuro-feedback derived from our analyses may provide useful cues for the effectiveness of neurostimulation.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Brain Mapping
  • Brain*
  • Humans
  • Neuronal Plasticity
  • Neurophysiology
  • Transcranial Direct Current Stimulation*