Cortical Stimulation Induces Network-Wide Coherence Change In Non-Human Primate Somatosensory Cortex

Annu Int Conf IEEE Eng Med Biol Soc. 2019 Jul:2019:6446-6449. doi: 10.1109/EMBC.2019.8856633.


Stimulation of the cortex can modulate the connectivity between brain regions. Although targeted neuroplasticity has been demonstrated in-vitro, in-vivo models have been inconsistent in their response to stimulation. In this paper, we tested various stimulation protocols to characterize the effect of stimulation on coherence in the non-human primate cortex in-vivo. We found that the stimulation latency, the state of the cortex during stimulation, and the stimulation site all affected the modulation of cortical coherence. We further investigated features of a resting-state network that could predict how a connection is likely to change with stimulation.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Animals
  • Brain Mapping
  • Neuronal Plasticity
  • Primates*
  • Somatosensory Cortex*