Strigolactones (SLs) are a class of plant hormones involved in several biological processes that are of great agricultural concern. While initiating plant-fungal symbiosis, SLs also trigger germination of parasitic plants that pose a major threat to farming. In vascular plants, SLs control shoot branching, which is linked to crop yield. SL research has been a fascinating field that has produced a variety of different signaling models, reflecting a complex picture of hormone perception. Here, we review recent developments in the SL field and the crystal structures that gave rise to various models of receptor activation. We also highlight the increasing number of discovered SL molecules, reflecting the existence of cross-kingdom SL communication.
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