Visualization of circular RNAs and their internal splicing events from transcriptomic data
- PMID: 31950978
- DOI: 10.1093/bioinformatics/btaa033
Visualization of circular RNAs and their internal splicing events from transcriptomic data
Abstract
Summary: Circular RNAs (circRNAs) are proved to have unique compositions and splicing events distinct from canonical mRNAs. However, there is no visualization tool designed for the exploration of complex splicing patterns in circRNA transcriptomes. Here, we present CIRI-vis, a Java command-line tool for quantifying and visualizing circRNAs by integrating the alignments and junctions of circular transcripts. CIRI-vis can be applied to visualize the internal structure and isoform abundance of circRNAs and perform circRNA transcriptome comparison across multiple samples.
Availability and implementation: https://sourceforge.net/projects/ciri/files/CIRI-vis.
Supplementary information: Supplementary data are available at Bioinformatics online.
© The Author(s) 2020. Published by Oxford University Press. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.
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