The Tumor Microbiome in Pancreatic Cancer: Bacteria and Beyond

Cancer Cell. 2019 Dec 9;36(6):577-579. doi: 10.1016/j.ccell.2019.11.004.


There is increasing appreciation of the microbial influence on cancer, with emerging evidence about the tumor microbiome and crosstalk with the gut microbiome. A great example of this is pancreatic cancer, in which intra-tumoral microbes such as bacteria and fungi have been shown to contribute to carcinogenesis and therapeutic responses, both positively and negatively.

Publication types

  • Research Support, N.I.H., Extramural
  • Review

MeSH terms

  • Bacteria / immunology*
  • Carcinogenesis / immunology
  • Gastrointestinal Microbiome / immunology*
  • Humans
  • Microbiota / immunology*
  • Pancreatic Neoplasms / immunology*
  • Pancreatic Neoplasms / pathology