Structure of an Arc-ane virus-like capsid

Nat Neurosci. 2020 Feb;23(2):153-154. doi: 10.1038/s41593-019-0580-3.

Abstract

Recent findings unveil a viral-like mechanism for the transmission of synaptic plasticity signals involving the activity-regulated cytoskeleton-associated protein (Arc). Arc forms capsid-like particles that package RNA and are transported across synapses. Here Erlendsson et al. present a high-resolution structural representation of Arc capsids, enabling deeper analysis of their function.

Publication types

  • Comment

MeSH terms

  • Animals
  • Capsid*
  • Drosophila
  • Neurons*