Re-evaluation of the effects of high PEEP with recruitment manoeuvres versus low PEEP without recruitment manoeuvres during general anaesthesia for surgery -Protocol and statistical analysis plan for an individual patient data meta-analysis of PROVHILO, iPROVE and PROBESE

N S Campos; T Bluth; S N T Hemmes; J Librero; N Pozo; C Ferrando; L Ball; G Mazzinari; P Pelosi; M Gama de Abreu; M J Schultz; A S Neto; para el Comité de en Redacción nombre de The Reevaluation of PEEP in Anesthesia Meta-Analysis los investigadores en nombre red de PROVHILO, iPROVE y PROBESE Investigadores e Investigadores de la Red PROVE

doi:10.1016/j.redar.2019.08.002

Re-evaluation of the effects of high PEEP with recruitment manoeuvres versus low PEEP without recruitment manoeuvres during general anaesthesia for surgery -Protocol and statistical analysis plan for an individual patient data meta-analysis of PROVHILO, iPROVE and PROBESE

Rev Esp Anestesiol Reanim (Engl Ed). 2020 Feb;67(2):76-89. doi: 10.1016/j.redar.2019.08.002. Epub 2020 Jan 16.

[Article in English, Spanish]

Authors

Affiliations

¹ Deptartment of Critical Care Medicine, Hospital Israelita Albert Einstein, São Paulo, Brasil; Cardio-Pulmonary Department, Pulmonary Division, Instituto do Coração, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de São Paulo, Sao Pãulo, Brasil.
² Pulmonary Engineering Group, Department of Anesthesiology and Intensive Care Medicine, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.
³ Department of Intensive Care & Laboratory of Experimental Intensive Care and Anesthesiology (LEICA), Amsterdam UMC, University of Amsterdam, Ámsterdam, Holanda; Department of Anaesthesiology, AnaesthesiologyDepartment Amsterdam UMC location 'AMC', University of Amsterdam, Ámsterdam, Países Bajos.
⁴ Navarrabiomed-Fundación Miguel Servet, Red de Investigación en Servicios de Salud en Enfermedades Crónicas (REDISSEC), Pamplona, Navarra, España.
⁵ Department of Anesthesiology and Critical Care, Hospital Clínic de Barcelona, Barcelona, España.
⁶ Department of Anesthesiology and Critical Care, Hospital Clínic de Barcelona, Barcelona, España; CIBER of Respiratory Disease, Instituto de Salud Carlos III, Madrid, España.
⁷ IRCCS San Martino Policlinico Hospital, Genoa, Italia; Department of Surgical Sciences and Integrated Diagnostics (DISC), University of Genoa, Genoa, Italia.
⁸ Department of Anesthesiology and Pain Medicine, Hospital de Manises, Valencia, España.
⁹ Department of Intensive Care & Laboratory of Experimental Intensive Care and Anesthesiology (LEICA), Amsterdam UMC, University of Amsterdam, Ámsterdam, Holanda; Research Group in Perioperative Medicine, Instituto de Investigación Sanitaria La Fe, Valencia, España; Mahidol Oxford Tropical Medicine Research Unit (MORU), Faculty of Tropical Medicine, Mahidol University, Bangkok, Tailandia.
¹⁰ Deptartment of Critical Care Medicine, Hospital Israelita Albert Einstein, São Paulo, Brasil; Cardio-Pulmonary Department, Pulmonary Division, Instituto do Coração, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de São Paulo, Sao Pãulo, Brasil; Department of Intensive Care & Laboratory of Experimental Intensive Care and Anesthesiology (LEICA), Amsterdam UMC, University of Amsterdam, Ámsterdam, Holanda. Electronic address: ary.neto2@einstein.br.

PMID: 31955891
DOI: 10.1016/j.redar.2019.08.002

No abstract available

Publication types

Comparative Study

MeSH terms

Aged
Anesthesia, General*
Female
Humans
Male
Meta-Analysis as Topic
Middle Aged
Positive-Pressure Respiration* / adverse effects
Positive-Pressure Respiration* / methods
Postoperative Complications / etiology
Randomized Controlled Trials as Topic* / methods
Sample Size