Platelet-rich plasma for the treatment of coccydynia: a case report and review of regenerative medicine for coccydynia

Regen Med. 2019 Dec;14(12):1151-1154. doi: 10.2217/rme-2019-0102. Epub 2020 Jan 21.


Aim: To describe the successful treatment of coccydynia using ultrasound-guided injection of platelet-rich plasma. Setting: Outpatient orthopedic practice. Patient: 17-year-old female with BMI of 42.6. Case description: The patient presented with 6 months of nontraumatic coccygeal pain exacerbated by sitting. Physical exam was significant for point-tenderness over the sacral hiatus and coccyx. A corticosteroid injection around the sacrococcygeal ligament was administered with immediate resolution of her pain following the injection with the anesthetic. The patient reported significant pain relief for 1 week. The superficial sacrococcygeal ligament was then treated with a platelet-rich plasma injection under US guidance. Results: The patient reported a 70% improvement in pain and sitting tolerance at 6 weeks. By 6 months post injection, her pain was 100% resolved, and she remained pain free at the 12-month follow-up. Conclusion: Platelet-rich plasma may be considered as a treatment option in patients with refractory coccydynia.

Keywords: coccydynia; platelet-rich plasma; regenerative medicine; ultrasound guided injection.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adolescent
  • Coccyx / physiopathology*
  • Female
  • Humans
  • Pain / prevention & control*
  • Platelet-Rich Plasma / cytology*
  • Regenerative Medicine*