Fulminant subacute sclerosing panencephalitis in association with pregnancy

Arch Neurol. 1988 Dec;45(12):1324-5. doi: 10.1001/archneur.1988.00520360042009.


Subacute sclerosing panencephalitis developed during pregnancy in a 27-year-old woman and immediately after delivery in an 18-year-old woman. In both, disease took an acute and fulminant course culminating in a vegetative state within several weeks. It is suggested that the relative older age of disease presentation and the unusually rapid neurologic deterioration were partially due to immunologic and hormonal alterations of pregnancy.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Adult
  • Aging
  • Antibodies, Viral / analysis
  • Coma / etiology
  • Coma / physiopathology
  • Female
  • Humans
  • Measles virus / immunology
  • Pregnancy
  • Pregnancy Complications, Infectious / physiopathology*
  • Subacute Sclerosing Panencephalitis / physiopathology*


  • Antibodies, Viral