Comparison of the effects of continuous negative external chest pressure and positive end-expiratory pressure on cardiac index in dogs

Am Rev Respir Dis. 1977 Jan;115(1):39-45. doi: 10.1164/arrd.1977.115.1.39.


Continuous negative external chest pressure was used to increase the functional residual capacity in 6 dogs, and the effects were compared with the effects of increasing functional residual capacity using positive end-expiratory pressure. Cardiac index and mixed venous O2 stauration each decreased from control values during positive end-expiratory pressure, but did not decrease with continuous negative external chest pressure. Continuous negative external chest pressure may provide an alternative to positive end-expiratory pressure for increasing the functional residual capacity of patients in whom the latter causes unacceptable decreases in venous return and cardiac output.

Publication types

  • Comparative Study

MeSH terms

  • Animals
  • Cardiac Output*
  • Dogs
  • Functional Residual Capacity
  • Oxygen / blood
  • Positive-Pressure Respiration*
  • Pressure
  • Respiration, Artificial*
  • Thorax / physiology*
  • Veins


  • Oxygen