Psoriasis and Co-morbidity

Acta Derm Venereol. 2020 Jan 30;100(3):adv00033. doi: 10.2340/00015555-3387.


Psoriasis is associated with multiple co-morbid medical conditions. The purpose of this study is to evaluate the relationships between psoriasis and cardiovascular disease, psoriatic arthritis, mental health conditions, and immune-mediated diseases, respectively. A literature search was performed during the study period January 1, 2015 to December 18, 2018. Of 2,499 records identified, 28 met our criteria selection and were included in this review. The relationships between psoriasis and these multiple comorbid disease conditions are discussed and are important to consider when developing the treatment plan and overall management of patients with psoriasis. Early recognition and treatment of comorbid disease conditions is important to help improve the quality of life for these patients.

Keywords: cardiovascular disease; depression; immune-mediated disease; mental health conditions; psoriasis; psoriatic arthritis.

Publication types

  • Review

MeSH terms

  • Arthritis, Psoriatic / epidemiology
  • Biological Products / therapeutic use
  • Cardiovascular Diseases / epidemiology*
  • Comorbidity
  • Humans
  • Immune System Diseases / epidemiology*
  • Mental Disorders / epidemiology*
  • Psoriasis / drug therapy*
  • Psoriasis / epidemiology*
  • Risk Factors


  • Biological Products