Diabetes mellitus is a metabolic disorder characterized by chronic hyperglycemia. About 589 million adults aged 20 to 79 years are living with diabetes globally as of 2025, and diabetes-related deaths are estimated at approximately 3 to 4 million annually. (Source:
Hemoglobin A1c (HbA1c) indicates mean blood glucose over 2 to 3 months. Both the American Diabetes Association (ADA) and the International Expert Committee recommend an HbA1c of 6.5% or greater for diabetes diagnosis. Each 1% increase in HbA1c increases peripheral vascular disease risk by 25% to 28%.
Patients with diabetes face an elevated risk of lower extremity amputation, increased healthcare costs, and reduced quality of life. In a systematic review of nontraumatic amputations among patients with diabetes and peripheral vascular disease, the 5-year mortality rate after below-the-knee amputation was 40% to 82%, and 40% to 90% following above-the-knee amputation. Many complications are preventable through annual foot examination and routine patient-performed foot care. This activity delves into the anatomy, indications, equipment, personnel, preparation, technique, complications, and clinical significance of diabetic foot care.
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