Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
, 18 (3), 166-173

The Influence of Concurrent Training Intensity on Serum Irisin and Abdominal Fat in Postmenopausal Women

Affiliations

The Influence of Concurrent Training Intensity on Serum Irisin and Abdominal Fat in Postmenopausal Women

Bita Azimi Rashti et al. Prz Menopauzalny.

Abstract

Introduction: Menopause seems to be among the factors related to the development of prediabetes and central obesity. Conversely, physical activity may have a major role in reducing metabolic syndrome in women of postmenopausal age.

Material and methods: Forty-eight postmenopausal active and sedentary women within the ages of 45-65 years were randomized to four groups: 1) high-intensity concurrent interval exercise (HCI; n = 15), 2) moderate-intensity continuous concurrent exercise (MCC; n = 14), 3) control daily active (CDA; n = 10), and 4) control sedentary (COS; n = 9). The subjects in the preceding training groups exercised three times per week for 50-65 min/session with high/moderate concurrent exercise for 10 weeks. The levels of serum irisin, insulin sensitivity, abdominal fat distribution (visceral and subcutaneous), and total abdominal fat were measured at baseline and post-test.

Results: This study showed that the HCI group had a significantly increased serum irisin (p< 0.001), stimulated favorable alterations in insulin sensitivity status (p = 0.003), and significantly decreased subcutaneous, visceral and, total abdominal fat (p< 0.001). Also, the insulin sensitivity status was significantly increased (p = 0.01) and subcutaneous abdominal fat significantly decreased in the MCC group (p = 0.018). However, this study's results did not find a considerable correlation between insulin sensitivity, irisin level, weight loss and abdominal fat distribution.

Conclusions: High-intensity concurrent exercise has a greater influence on improving most metabolic-related parameters than moderate-intensity concurrent exercise.

Keywords: abdominal fat; concurrent exercise; insulin sensitivity; irisin; postmenopausal women.

Conflict of interest statement

The authors report no conflicts of interest.

Figures

Fig. 1
Fig. 1
Inclusion process for analysis; high-intensity concurrent interval exercise (HCI), moderate-intensity continuous concurrent exercise (MCC), control daily active (CDA), and control sedentary (COS)
Fig. 2
Fig. 2
Inclusion process for analysis; high-intensity concurrent interval exercise (HCI), moderate-intensity continuous concurrent exercise (MCC), control daily active (CDA), and control sedentary (COS)

Similar articles

See all similar articles

References

    1. Kozakowski J, Gietka CM, Leszczyńska D, Majos A. Obesity in menopause our negligence or an unfortunate inevitability? Prz Menopauzalny 2017; 16: 61-65. - PMC - PubMed
    1. Lee IM, Shiroma EJ, Lobelo F, et al. Effect of physical inactivity on major non-communicable diseases worldwide: an analysis of burden of disease and life expectancy. Lancet 2012; 380: 219-229. - PMC - PubMed
    1. Velders M, Diel P. How sex hormones promote skeletal muscle regeneration. Sports Med 2013; 43: 1089-1100. - PubMed
    1. Mourier A, Gautier JF, De Kerviler E, et al. Mobilization of visceral adipose tissue related to the improvement in insulin sensitivity in response to physical training in NIDDM: effects of branched-chain amino acid supplements. Diabetes Care 1997; 20: 385-391. - PubMed
    1. Pekkala S, Wiklund PK, Hulmi JJ, et al. Are skeletal muscle FNDC5 gene expression and irisin release regulated by exercise and related to health? J Physiol 2013; 591: 5393-5400. - PMC - PubMed

LinkOut - more resources

Feedback