In December 2019, a cluster of patients with pneumonia of unknown cause was linked to a seafood wholesale market in Wuhan, China. A previously unknown betacoronavirus was discovered through the use of unbiased sequencing in samples from patients with pneumonia. Human airway epithelial cells were used to isolate a novel coronavirus, named 2019-nCoV, which formed another clade within the subgenus sarbecovirus, Orthocoronavirinae subfamily. Different from both MERS-CoV and SARS-CoV, 2019-nCoV is the seventh member of the family of coronaviruses that infect humans. Enhanced surveillance and further investigation are ongoing. (Funded by the National Key Research and Development Program of China and the National Major Project for Control and Prevention of Infectious Disease in China.).
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Genomic Characterisation and Epidemiology of 2019 Novel Coronavirus: Implications for Virus Origins and Receptor BindingR Lu et al. Lancet. PMID 32007145.National Key Research and Development Program of China, National Major Project for Control and Prevention of Infectious Disease in China, Chinese Academy of Sciences, Sha …
Genomic Characterization of the 2019 Novel Human-Pathogenic Coronavirus Isolated From a Patient With Atypical Pneumonia After Visiting WuhanJF Chan et al. Emerg Microbes Infect 9 (1), 221-236. PMID 31987001.A mysterious outbreak of atypical pneumonia in late 2019 was traced to a seafood wholesale market in Wuhan of China. Within a few weeks, a novel coronavirus tentatively n …
Potential Maternal and Infant Outcomes From (Wuhan) Coronavirus 2019-nCoV Infecting Pregnant Women: Lessons From SARS, MERS, and Other Human Coronavirus InfectionsDA Schwartz et al. Viruses 12 (2). PMID 32050635.In early December 2019 a cluster of cases of pneumonia of unknown cause was identified in Wuhan, a city of 11 million persons in the People's Republic of China. Further i …
Overlapping and Discrete Aspects of the Pathology and Pathogenesis of the Emerging Human Pathogenic Coronaviruses SARS-CoV, MERS-CoV, and 2019-nCoVJ Liu et al. J Med Virol. PMID 32056249. - ReviewFirst reported from Wuhan, PR China, on 31 December 2019, the ongoing outbreak of a novel coronavirus (2019-nCoV) causes great global concerns. Based on the advice of the …
[Coronaviruses as the Cause of Respiratory Infections]VM Corman et al. Internist (Berl) 60 (11), 1136-1145. PMID 31455974. - ReviewAll six human CoVs can be diagnosed using RT-PCR on respiratory specimens but this is rarely necessary for the four endemic strains. In current clinical practice SARS-CoV …
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The Role of Augmented Intelligence (AI) in Detecting and Preventing the Spread of Novel CoronavirusJB Long et al. J Med Syst 44 (3), 59. PMID 32020374.