Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
, 29 (9), 1173-9

Colonic Mass Movements in Idiopathic Chronic Constipation


Colonic Mass Movements in Idiopathic Chronic Constipation

G Bassotti et al. Gut.


As relatively little is known of human colonic motor activity either in health, or in pathological conditions, we investigated mass movements in 14 chronically constipated patients and 18 healthy volunteers. Mass movements were recorded from proximal and distal colon during 24 h (12 noon-12 noon) by a colonoscopically positioned multilumen manometric probe and low compliance infusion system. Patients and controls differed significantly in the number (mean 2.6 (0.7) v 6.1 (0.9) (SE), p = 0.02) and duration (mean 8.2 (1.6) v 14.1 (0.8) s, p = 0.04) of mass movements. The data suggest that one pathophysiological mechanism of constipation may be decreased propulsive activity. A circadian pattern, with a significant difference between day and night distribution, was documented in both groups. The patients reported decreased defecatory stimulus concomitant with the mass movements.

Similar articles

See all similar articles

Cited by 52 PubMed Central articles

See all "Cited by" articles


    1. Gastroenterol Clin Biol. 1985 Jun-Jul;9(6-7):480-5 - PubMed
    1. Gut. 1968 Aug;9(4):442-56 - PubMed
    1. Arch Intern Med. 1986 Apr;146(4):716-20 - PubMed
    1. Gut. 1986 Sep;27(9):995-8 - PubMed
    1. Gut. 1970 Feb;11(2):91-9 - PubMed