Aberrant global and local efficiency of the executive subnetwork in essential tremor

J Neural Transm (Vienna). 2020 Mar;127(3):385-388. doi: 10.1007/s00702-020-02141-x. Epub 2020 Jan 25.

Abstract

This study aims to use probabilistic tractography to ascertain the global (GE) and local efficiency (LE) of the executive subnetwork in essential tremor (ET). Significantly lower GE of the whole executive subnetwork and lower LE of the left rostral middle frontal gyrus, frontal pole, inferior frontal gyrus, bilateral anterior cingulate cortex, and medial orbitofrontal cortex. These results imply ineffective and inadequate communication of the executive subnetwork, and may be causally associated with the executive dysfunction observed in ET.

Keywords: Essential tremor; Executive; Structural connectivity; Tremor.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Diffusion Magnetic Resonance Imaging
  • Essential Tremor* / diagnostic imaging
  • Essential Tremor* / pathology
  • Essential Tremor* / physiopathology
  • Executive Function* / physiology
  • Female
  • Gyrus Cinguli* / diagnostic imaging
  • Gyrus Cinguli* / pathology
  • Gyrus Cinguli* / physiopathology
  • Humans
  • Male
  • Middle Aged
  • Nerve Net* / diagnostic imaging
  • Nerve Net* / pathology
  • Nerve Net* / physiopathology
  • Prefrontal Cortex* / diagnostic imaging
  • Prefrontal Cortex* / pathology
  • Prefrontal Cortex* / physiopathology