Recurrent endobronchial inflammatory myofibroblastic tumors: Novel treatment options

Pediatr Pulmonol. 2020 Mar;55(3):788-790. doi: 10.1002/ppul.24666. Epub 2020 Jan 27.

Abstract

Endobronchial inflammatory myofibroblastic tumors (IMTs) rarely occur in children younger than 10 years of age and have intermediate malignant potential. A 7-year-old girl initially presented with pneumonia. After failing outpatient treatment, she re-presented in status asthmaticus. Computed tomography showed a left mainstem endobronchial mass which was resected bronchoscopically. Pathology was consistent with IMT. Surveillance bronchoscopy identified a recurrence. Despite a left upper lobectomy, recurrence led to further treatment with celecoxib and argon plasma coagulation. Follow-up bronchoscopy revealed complete resolution. She remains disease and symptom-free at her six-year follow-up.

Keywords: endobronchial tumor; inflammatory myofibroblastic tumor.

Publication types

  • Case Reports

MeSH terms

  • Anti-Inflammatory Agents, Non-Steroidal / therapeutic use
  • Argon Plasma Coagulation
  • Bronchoscopy
  • Celecoxib / therapeutic use
  • Child
  • Female
  • Granuloma, Plasma Cell / diagnosis
  • Granuloma, Plasma Cell / therapy*
  • Humans
  • Recurrence
  • Tomography, X-Ray Computed

Substances

  • Anti-Inflammatory Agents, Non-Steroidal
  • Celecoxib