A large outbreak of mumps in the postvaccine era

J Infect Dis. 1988 Dec;158(6):1253-60. doi: 10.1093/infdis/158.6.1253.

Abstract

During a county-wide mumps outbreak in Nashville, Tennessee, 332 cases of mumps were identified at a public high school (attack rate, 18.8%). A pep rally 17 d before the peak of the outbreak at a single public high school may have provided an opportunity for point-source exposure. A case-control study demonstrated that vaccine efficacy was 75% (we used provider-verified records and excluded students with a history of mumps disease). Although school records were nonuniform, mumps immunization status was correct, compared with provider-verified records, in at least 85% of both cases and controls. Parental reports were much less reliable. The cost of the outbreak was estimated at $154/case. Receiving mumps vaccine at a vaccine clinic held after the outbreak had peaked was associated with a decrease in risk of mumps disease. Thus, these clinics may have a role in the control of such outbreaks.

MeSH terms

  • Adolescent
  • Child
  • Costs and Cost Analysis
  • Disease Outbreaks*
  • Female
  • Humans
  • Immunization*
  • Male
  • Mumps / economics
  • Mumps / epidemiology*
  • Mumps Vaccine
  • Risk Factors
  • Tennessee

Substances

  • Mumps Vaccine