Ginger and avocado as nutraceuticals for obesity and its comorbidities

Phytother Res. 2020 Jun;34(6):1282-1290. doi: 10.1002/ptr.6619. Epub 2020 Jan 27.

Abstract

Obesity is a worldwide epidemic and is one of the factors involved in the etiology of type 2 diabetes mellitus. Obesity induces low-grade inflammation and oxidative stress. The treatment for obesity involves changes in diet, physical activity, and even medication and surgery. Currently, the use of nutraceutical compounds is associated with health benefits. Ginger and avocado are used for many people all around the world; however, its effect as a nutraceutical compound is less known by the general population. For this reason, we searched information of the literature to point its effects on distinct mechanisms of defense against the obesity its comorbidities. The present review aimed showing that these nutraceuticals may be useful in obesity treatment. Reports have shown that ginger and avocado induce antioxidant and anti-inflammatory effects by improving enzymatic activity and modulating obesity-related impairments in the anti-inflammatory system in different tissues, without side effects. Furthermore, ginger and avocado were found to be effective in reversing the harmful effects of obesity on blood lipids. In conclusion, on the basis of the positive effects of ginger and avocado in in vitro, animal, and human studies, these nutraceuticals may be useful in obesity treatment.

Keywords: diabetes treatment; inflammation; obesity; oxidative stress; phytotherapeutic approach; unhealthy diet.

Publication types

  • Review

MeSH terms

  • Animals
  • Anti-Obesity Agents / pharmacology
  • Anti-Obesity Agents / therapeutic use*
  • Dietary Supplements / analysis*
  • Ginger / chemistry*
  • Humans
  • Obesity / drug therapy*
  • Persea / chemistry*

Substances

  • Anti-Obesity Agents