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Comparative Study
. 2020 Jan 28;323(4):374-376.
doi: 10.1001/jama.2019.20008.

First-Trimester Pregnancy Exposure to Modafinil and Risk of Congenital Malformations

Per Damkier  1 , Anne Broe  1
Affiliations
Comparative Study

First-Trimester Pregnancy Exposure to Modafinil and Risk of Congenital Malformations

Per Damkier et al. JAMA. .

Abstract

This study uses pharmacoepidemiology data from Danish national health registries to examine the association between first-trimester exposure to modafinil and risk of major congenital malformations.

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Conflict of interest statement

Conflict of Interest Disclosures: None reported.

Figures

Figure.
Figure.. Risk of Congenital Malformations From First-Trimester Modafinil Exposure
Odds ratios and 95% CIs comparing first-trimester exposure to modafinil with those who were unexposed and with those who were exposed to methylphenidate. Those who were methylphenidate exposed are also compared with those who were unexposed.
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