αIIb-Integrin (CD41) associated with blood eosinophils is a potential biomarker for disease activity in eosinophilic esophagitis

J Allergy Clin Immunol. 2020 Jun;145(6):1699-1701. doi: 10.1016/j.jaci.2020.01.022. Epub 2020 Jan 28.

Abstract

After EoE treatment, association of platelets with blood eosinophils, as reported by CD41, predicted esophageal eosinophil count. Percentage CD41+ circulating eosinophils is a potential non-invasive biomarker for EoE disease activity.

Publication types

  • Letter
  • Research Support, N.I.H., Extramural

MeSH terms

  • Adult
  • Biomarkers / blood*
  • Eosinophilic Esophagitis / blood*
  • Eosinophilic Esophagitis / immunology*
  • Eosinophils / immunology*
  • Esophagus / immunology*
  • Female
  • Humans
  • Male
  • Platelet Membrane Glycoprotein IIb / immunology*

Substances

  • Biomarkers
  • Platelet Membrane Glycoprotein IIb