ESPEN guideline on clinical nutrition in acute and chronic pancreatitis

Clin Nutr. 2020 Mar;39(3):612-631. doi: 10.1016/j.clnu.2020.01.004. Epub 2020 Jan 22.


Both acute and chronic pancreatitis are frequent diseases of the pancreas, which, despite being of benign nature, are related to a significant risk of malnutrition and may require nutritional support. Acute necrotizing pancreatitis is encountered in 20% of patients with acute pancreatitis, is associated with increased morbidity and mortality, and may require artificial nutrition by enteral or parenteral route, as well as additional endoscopic, radiological or surgical interventions. Chronic pancreatitis represents a chronic inflammation of the pancreatic gland with development of fibrosis. Abdominal pain leading to decreased oral intake, as well as exocrine and endocrine failure are frequent complications of the disease. All of the above represent risk factors related to malnutrition. Therefore, patients with chronic pancreatitis should be considered at risk, screened and supplemented accordingly. Moreover, osteoporosis and increased facture risk should be acknowledged in patients with chronic pancreatitis, and preventive measures should be considered.

Keywords: Acute pancreatitis; Chronic pancreatitis; Medical nutrition; Nutrition; Nutritional support; Pancreatic diseases.

Publication types

  • Practice Guideline
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acute Disease
  • Europe
  • Humans
  • Malnutrition / complications*
  • Malnutrition / prevention & control*
  • Nutritional Status*
  • Nutritional Support / methods*
  • Pancreatitis / complications*
  • Pancreatitis, Chronic
  • Societies, Medical