IQ-TREE 2: New Models and Efficient Methods for Phylogenetic Inference in the Genomic Era

Mol Biol Evol. 2020 May 1;37(5):1530-1534. doi: 10.1093/molbev/msaa015.


IQ-TREE (, last accessed February 6, 2020) is a user-friendly and widely used software package for phylogenetic inference using maximum likelihood. Since the release of version 1 in 2014, we have continuously expanded IQ-TREE to integrate a plethora of new models of sequence evolution and efficient computational approaches of phylogenetic inference to deal with genomic data. Here, we describe notable features of IQ-TREE version 2 and highlight the key advantages over other software.

Keywords: maximum likelihood; models of sequence evolution; phylogenetics; phylogenomics.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Evolution, Molecular*
  • Genomics*
  • Models, Genetic*
  • Phylogeny*
  • Software*