Cardiac uptake patterns in routine 18F-FDG PET-CT scans: A pictorial review

J Nucl Cardiol. 2020 Aug;27(4):1296-1305. doi: 10.1007/s12350-020-02049-9. Epub 2020 Feb 3.


Broad variability of 18F-Fluoro-2-deoxyglucose (FDG) uptake is noted in myocardium while performing FDG PET-CT scans for viability, infection, or oncologic purposes. While most of the uptakes are considered non-specific, presence of underlying cardiac disease is seldom encountered. With this presentation, our intent is to pictorially highlight the variable FDG uptake patterns associated with the normal variations, benign, and malignant disease.

Keywords: PET; diagnostic and prognostic application; image guided application.

Publication types

  • Review

MeSH terms

  • Cardiomyopathies / diagnostic imaging
  • Fluorodeoxyglucose F18 / pharmacokinetics*
  • Heart Neoplasms / diagnostic imaging
  • Humans
  • Myocardium / metabolism*
  • Myxoma / diagnostic imaging
  • Positron Emission Tomography Computed Tomography
  • Radiopharmaceuticals / pharmacology*


  • Radiopharmaceuticals
  • Fluorodeoxyglucose F18