Measures for diagnosing and treating infections by a novel coronavirus responsible for a pneumonia outbreak originating in Wuhan, China

Microbes Infect. 2020 Mar;22(2):74-79. doi: 10.1016/j.micinf.2020.01.003. Epub 2020 Feb 1.

Abstract

On 10 January 2020, a new coronavirus causing a pneumonia outbreak in Wuhan City in central China was denoted as 2019-nCoV by the World Health Organization (WHO). As of 24 January 2020, there were 887 confirmed cases of 2019-nCoV infection, including 26 deaths, reported in China and other countries. Therefore, combating this new virus and stopping the epidemic is a matter of urgency. Here, we focus on advances in research and development of fast diagnosis methods, as well as potential prophylactics and therapeutics to prevent or treat 2019-nCoV infection.

Keywords: 2019-nCoV; Diagnosis; Preventive; Therapeutic.

Publication types

  • Review

MeSH terms

  • Amino Acid Sequence
  • Antibodies, Neutralizing / immunology
  • Antibodies, Viral / immunology
  • Antiviral Agents / therapeutic use
  • Betacoronavirus / isolation & purification
  • Betacoronavirus / pathogenicity*
  • China / epidemiology
  • Clinical Laboratory Techniques
  • Coronavirus Infections / diagnosis*
  • Coronavirus Infections / drug therapy
  • Coronavirus Infections / therapy*
  • Humans
  • Nucleic Acid Amplification Techniques
  • Pneumonia, Viral / diagnosis*
  • Pneumonia, Viral / therapy*
  • RNA, Viral / analysis
  • Sequence Alignment
  • Spike Glycoprotein, Coronavirus / immunology
  • Viral Vaccines / immunology
  • Viral Vaccines / therapeutic use

Substances

  • Antibodies, Neutralizing
  • Antibodies, Viral
  • Antiviral Agents
  • RNA, Viral
  • Spike Glycoprotein, Coronavirus
  • Viral Vaccines

Supplementary concepts

  • COVID-19
  • COVID-19 diagnostic testing
  • COVID-19 drug treatment
  • severe acute respiratory syndrome coronavirus 2