Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro

Cell Res. 2020 Mar;30(3):269-271. doi: 10.1038/s41422-020-0282-0. Epub 2020 Feb 4.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adenosine Monophosphate / analogs & derivatives*
  • Adenosine Monophosphate / pharmacology
  • Adenosine Monophosphate / therapeutic use
  • Alanine / analogs & derivatives*
  • Alanine / pharmacology
  • Alanine / therapeutic use
  • Animals
  • Antimalarials* / pharmacology
  • Antimalarials* / therapeutic use
  • Antiviral Agents* / pharmacology
  • Antiviral Agents* / therapeutic use
  • Betacoronavirus / drug effects*
  • Betacoronavirus / pathogenicity
  • Biological Assay
  • Chlorocebus aethiops
  • Chloroquine* / pharmacology
  • Chloroquine* / therapeutic use
  • Coronavirus Infections / drug therapy*
  • Drug Discovery
  • Drug Evaluation, Preclinical
  • Humans
  • Middle East Respiratory Syndrome Coronavirus / drug effects
  • Pneumonia, Viral / drug therapy*
  • SARS Virus / drug effects
  • Sincalide
  • Vero Cells

Substances

  • Antimalarials
  • Antiviral Agents
  • remdesivir
  • Adenosine Monophosphate
  • Chloroquine
  • Sincalide
  • Alanine

Supplementary concepts

  • COVID-19
  • COVID-19 drug treatment
  • severe acute respiratory syndrome coronavirus 2