Asherman syndrome in adenomyosis treated with uterine artery embolization: incidence predictive factors

Radiol Med. 2020 May;125(5):437-443. doi: 10.1007/s11547-020-01136-8. Epub 2020 Feb 4.

Abstract

Purpose: To investigate Asherman syndrome (AS) related to potential factors during uterine artery embolization (UAE) treatment of adenomyosis.

Materials and methods: This is a retrospective analysis of 195 women with adenomyosis who underwent UAE treatment from 2009 to 2016. All preoperative and intraoperative risk-related potential factors of AS were recorded. And AS events were carefully monitored during follow-up (range, 0-15 months). Potential risk-related factors of AS events were determined via univariate and multivariate logistic regression analyses.

Results: The rate of AS events after UAE for adenomyosis was 12.82% (25/195). The univariate and multivariate analyses revealed the association of low vascularity with a significant risk for AS (P = 0.019).

Conclusion: Patients with low vascularity of adenomyosis at the time of UAE are more likely to have AS. And adenomyosis patients with low vascularity should be carefully selected to undergo UAE treatment.

Keywords: Adenomyosis; Angiography; Asherman syndrome; UAE.

MeSH terms

  • Adenomyosis / diagnostic imaging
  • Adenomyosis / therapy*
  • Adult
  • Analysis of Variance
  • Angiography, Digital Subtraction
  • Endometrium / blood supply
  • Female
  • Follow-Up Studies
  • Gynatresia / etiology*
  • Humans
  • Middle Aged
  • Organ Size
  • Retrospective Studies
  • Risk Factors
  • Syndrome
  • Uterine Artery Embolization / adverse effects*
  • Uterine Artery Embolization / methods
  • Uterus / blood supply
  • Young Adult