Objectives: This report provides information on 14 behavioral and nutritional factors, needed for stomach cancer prevention programs.
Methods: PubMed, Web of Science, and Scopus databases were searched until December 2018. The reference lists were screened too. Observational studies addressing the association between stomach cancer and behavioral factors were enrolled. The heterogeneity between studies was investigated using Chi2, Tau2, and I2 statistic. The likelihood of publication bias was explored using Begg's and Egger's tests and Trim & Fill analysis. The effect szie were expressed as the odds ratio (OR) with 95% confidence intervals (CI) using a random-effects model.
Results: Of 52,916 identified studies, 232 were eligible involving 33,831,063 participants. The OR (95% CI) of factors associated with stomach cancer was as follows: H. pylori infection 2.56 (2.18, 3.00); currently smoking 1.61 (1.49, 1.75); formerly smoked 1.43 (1.29, 1.59); currently drinking 1.19 (1.10, 1.29); formerly drank 1.73 (1.17, 2.56); overweight/obesity 0.89 (0.74, 1.08); sufficient physical activity 0.83 (0.68, 1.02); intake of fruits ≥3 times/week 0.48 (0.37, 0.63); intake of vegetables ≥3 times/week 0.62 (0.49, 0.79); using pickled vegetables 1.28 (1.09, 1.51); black tea 1.00 (0.84, 1.20); green tea 0.88 (0.80, 0.97); coffee 0.99 (0.88, 1.11); using fish ≥1 time/week 0.79 (0.61, 1.03); using red meat ≥4 times/week 1.31 (0.87, 1.96), and high salt intake.
Conclusion: This meta-analysis provided a clear picture of behavioral and nutritional factors playing pivotal roles in developing stomach cancer. These results may be utilized for ranking and prioritizing preventable risk factors to implement effective prevention programs.
Keywords: Behavior; Gastric Cancer; Meta-analysis; Nutrition; Risk Factors; Stomach Neoplasms.
Smoking and Suicide: A Meta-AnalysisJ Poorolajal et al. PLoS One 11 (7), e0156348. PMID 27391330. - Meta-AnalysisThere is sufficient evidence that smoking is associated with an increased risk of suicidal behaviors. Therefore, smoking is a contributing factor for suicide. Although th …
The Association Between Body Mass Index and Preeclampsia: A Meta-AnalysisJ Poorolajal et al. J Matern Fetal Neonatal Med 29 (22), 3670-6. PMID 26762770. - Meta-AnalysisThere is sufficient evidence that excess body mass index is significantly associated with an increased risk of preeclampsia. Therefore, overweight and obesity can be cons …
Landscape of Dietary Factors Associated With Risk of Gastric Cancer: A Systematic Review and Dose-Response Meta-Analysis of Prospective Cohort StudiesX Fang et al. Eur J Cancer 51 (18), 2820-32. PMID 26589974. - ReviewThis study provides comprehensive and strong evidence that there are a number of protective and risk factors for gastric cancer in diet. Our findings may have significant …
Effect of Smoking on Multiple Sclerosis: A Meta-AnalysisJ Poorolajal et al. J Public Health (Oxf) 39 (2), 312-320. PMID 27160862. - ReviewSmoking habits are significantly associated with MS, although the association is not very strong. However, there is a dose-response relationship between the smoking habit …
Coffee Consumption and the Risk of Gastric Cancer: A Meta-Analysis of Prospective Cohort StudiesL Li et al. BMC Cancer 15, 733. PMID 26481317. - ReviewThis meta-analysis does not support the hypothesis that coffee consumption is associated with the risk of gastric cancer. The increased risk of gastric cancer for partici …